Prof Danny McAuley chairs a panel discussion between the investigators of the trials presented in detail at day 1 of the Critical Care Reviews Meeting 2019 - POPPI (Prof Kathy Rowan), MIND-USA (Assoc Prof Timoth Girard), AI in Sepsis (Prof Anthony Gordon), ANDROMEDA-SHOCK (Prof Jan Bakker), SMART (Prof Todd Rice) and APPROCCHSS (Prof Djillali Annane)