Dr Francois Lamontagne joins Rob Mac Sweeney to discuss the harmonised REMAP-CAP / LOVIT-COVID vitamin C trial. The trial was presented at the European Society of Intensive Care Medicine annual congress and simultaneously published in the New England Journal of Medicine.

Scott Berry (Austin) and Danny McAuley (Belfast) join Rob Mac Sweeney to discuss the results of the statin domain of the REMAP-CAP trial, investigating 80mg once daily of simvastatin in critically ill patients with COVID-19.

Prof Alistair Nichol (Dublin & Melbourne) discusses why the REMAP-CAP adaptive platform trial has chosen to investigate ivermectin, given the controversy surrounding this agent.

Dr Lennie Derde is the Trial Steering Committee Chair and the European Coordinating Investigator for the REMAP-CAP project. She discusses the running of the REMAP-CAP trial, her background in critical care and infectious diseases, how she got into critical care research, the background of the REMAP-CAP trial and its current workload for her. We also review the output from the trial to date and finish by considering how this pandemic is likely to progress.

Prof Derek Angus, from Pittsburgh, USA, discusses a modern healthcare system which merges research into clinical practice, producing a "learning while doing" healthcare model.

In the latest episode on the REMAP-CAP series, Prof Alistair Nichol (Dublin / Melbourne) discuss the upcoming ventilation domain with Rob Mac Sweeney.

Mathias Pletz discusses pandemics and the role of REMAP-CAP adaptive platform trial in responding to the COVID-19 pandemic

Scott Berry discusses the methodological and statistical framework behind the REMAP-CAP trial

Prof Steve Webb, from Perth, Australia, discusses the origin, design and execution of the REMAP-CAP adaptive platform trial