Rob Mac Sweeney chats with Jessica Spence about the B-FREE trial, investigating benzodiazepine-free anaesthesia for the prevention of delirium in cardiac surgery

Prof Mark Peters, from Great Ormond Street Hospital, delivers an editorial on the NITRIC trial, investigating nitric oxide during cardiac surgery for children with congenital cardiac disease. The chief investigator for the trial Assoc Prof Luregn Schlapbach replies.

Assoc Prof Luregn Schlapbach (Zurich, Switzerland) presents the results of the NITRIC trial, investigating nitric oxide during cardiac surgery for children with congenital cardiac disease.

Rob Mac Sweeney hosts a panel discussion on the results of the FIRST ABC trial, comparing HFNO with CPAP in recently extubated children. The panelists are Martha A.Q. Curley (Philadelphia), Christopher M. Horvat (Pittsburgh), Martin Kneyber (Groningen), and David Harrison (London). They are joined by Padmanabhan Ramnarayan (chief investigator), Alvin Richards-Belle (trial manager) and Adrienne Randolph (editorialist).

Chris Nutt (Belfast) asks the chief investigator of the FIRST-ABC trial Padmanabhan Ramnarayan (London) questions from the viewers during the livestream presentation of the trial results.

Dr Padmanabhan Ramnarayan (London) and Mr Alvin Richards-Belle (London) present the results of the FIRST-ABC (Step Down) trial, comparing high flow nasal oxygen with continuous positive airway pressure in recently extubated children.

Naomi Hammond and Simon Finfer join Rob Mac Sweeney to discuss the reaction of the critical care community to the presentation and publication of both the PLUS trial and the systematic review and meta analysis comparing balanced solutions with 0.9% saline in the critically ill.

Dr Rob Mac Sweeney (Belfast, Northern Ireland) chairs a panel discussion on the results of the BOUGIE trial, comparing the use of a stylet with a bougie in 1102 patients requiring emergency intubation in either the emergency department or the ICU. The panelists are Prof Jonathan Benger (Bristol, England), Dr George Kovacs (Halifax, Canada), Dr Jean-Baptiste (Nantes, France) and Prof Sheila Myatra (Mumbai, India). They are joined by the trialists Dr Jon Casey (Nasville, USA), Dr Stacy Trent (Denver, USA), Dr Brian Driver (Minneapolis, USA) & Dr Matt Semler (Nashville, USA).

Dr Chris Nutt (Belfast, Northern Ireland) asks questions posed by viewers of the BOUGIE trial results presentation livestream. These are answered by Dr Matt Semler (Nashville, USA) and Dr Brian Driver (Minneapolis, USA). Prof Jonathan Benger (Bristol, England) also joins the discussion.

Prof Sheila Myatra (Mumbai, India) delivers an independent editorial on the BOUGIE trial, comparing the use of a stylet with a bougie in 1102 patients requiring emergency intubation in the emergency department or the ICU. Dr Matt Semler (Nashville, USA) and Dr Brian Driver (Minneapolis, USA) reply to the editorial and Prof Jonathan Benger (Bristol, England) also joins the discussion.

Dr Jon Casey (Nasville, USA), Dr Stacy Trent (Denver, USA) and Dr Brian Driver (Minneapolis, USA) present the results of the BOUGIE trial at a Critical Care Reviews Trial Results Livestream, on December 8th, 2021. The BOUGIE trial compared the use of a stylet with a bougie in 1102 patients requiring emergency intubation in the emergency department or the ICU.

Dr Bharath Kumar presents preliminary results of the HOPE trial and discusses the difficulties of undertaking research during a pandemic.

Bram Rochwerg (Hamilton, Canada), Paul Mouncey (London, England) & Colin McArthur (Auckland, New Zealand) join trialists Sheila Nainan Myatra (Mumbai, India), Bala Ventakesh (Brisbane, Australia) and Anders Perner (Copenhagen, Denmark), as well as editorialists Marion Campbell (Aberdeen, Scotland), to discuss the COVID STEROID 2 trial.

Chris Nutt (Belfast) asks investigators Sheila Nainan Myatra, Bala Venkatesh & Anders Perner questions from the viewers during the D STEROID 2 Trial Results Presentation. This trial result was presented at a Critical Care Reviews Trial Results Livestream, on October 21st, 2021

Prof Marion Campbell (Aberdeen, Scotland) delivers an editorial on the COVID STEROID 2 Trial, comparing 12mg with 6mg of dexamethasone in patients with severe COVID-19 and hypoxia, at a Critical Care Reviews Trial Result Livestream, on October 21st, 2021.

Sheila Nainan Myatra (Mumbai, India), Bala Ventakesh (Brisbane, Australia), Anders Perner (Copenhagen, Denmark) present the results of the COVID STEROID 2 Trial, comparing 12mg with 6mg of dexamethasone in patients with severe COVID-19 and hypoxia, at a Critical Care Reviews Trial Result Livestream, on October 21st, 2021.

Chief investigator Lars Andersen joins Rob Mac Sweeney to address some of the questions and comments that arose following the presentation and publication of the VAM-IHCA trial results, investigating vasopressin and methylprednisolone for in-hospital cardiac arrest.

Rob Mac Sweeney (Belfast) hosts an expert panel to discuss the findings of the VAM-IHCA trial, investigating vasopressin and methylprednisolone for in-hospital cardiac arrest. The panel consists of Katherine Berg (Boston), Bernd Botttiger (Cologne), Ranjit Lall (Coventry), Louise Morrison (Toronto), Spyros Mentzelopoulos (Athens), Lars Wiuff Andersen & Asger Granfeldt (Aarhus), and Spyros Mentzelopoulos (Athens). This trial result was presented at a Critical Care Reviews Trial Results Livestream, on September 29th, 2021.

Chris Nutt (Belfast) poses questions from the viewers to the lead investigators of the VAM-IHCA trial, Lars Wiuff Andersen and Asger Granfeldt. This trial result was presented at a Critical Care Reviews Trial Results Livestream, on September 29th, 2021.

Prof Spyros Mentzelopoulos (Athens, Greece) delivers an independent editorial on the VAM-IHCA trial, investigating vasopressin and methylprednisolone for in-hospital cardiac arrest. This trial result was presented at a Critical Care Reviews Trial Results Livestream, on September 29th, 2021

Asger Granfeldt & Lars Wiuff Andersen (Aarhus, Denmark) present the results of the VAM-IHCA trial, investigating the combination of vasopressin and methylprednisolone for in-hospital cardiac arrest. This trial result was presented at a Critical Care Reviews Trial Results Livestream, on September 29th, 2021.

Prof Stephen Bernard (Melbourne) delivers an editorial on the TTM2 trial result, delivered as part of the Critical Care Reviews hosted TTM2 Trial Results Livestream.