Derek Russell (Birmingham, USA) and Jon Casey (Nashville, USA) presents the results of the PREPARE II trial, investigating fluid bolus therapy for the prevention of cardiovascular collapse during emergency intubation. Anthony Gordon (London, England) delivers an editorial, which is followed by a panel discussion including Lennie Derde (Utrecht, the Netherlands), Andrew Althouse (Pittsburgh, USA), Elizabeth Wilcox (Toronto, Canada) and Lars Andersen (Aarhous, Denmark). The session is chaired by Chris Seymour from the USA. PREPARE II was simultaneously published in JAMA.