Matthew Semler presents the results of the PILOT trial, comparing low, intermediate and high oxygenation targets in critically ill mechanically ventilated patients. Paul Young delivers an editorial and Chris Nutt asks questions from the viewers. The expert panel discussion includes Victoria Cornelius, Angelique de Man, Bodil Steen Rasmussen and Gilles Capellier. The paper was simultaneously published in the New England Journal of Medicine.

Lars Andersen (Aarhus, Denmark) presents the VAM-IHCA trial on June 15th at the Critical Care Reviews Meeting 2022, in Titanic Belfast. The VAM-IHCA trial investigates the combination of vasopressin and methylprednisolone in in-hospital cardiac arrest. Chris Seymour (Pittsburgh, USA) delivers an editorial after the trial presentation. The session is chaired by Catriona Kelly (Dublin, Ireland).

Rob Mac Sweeney (Belfast, Northern Ireland) hosts a panel discussion including Prof Paul Checchia (Houston, USA), Prof Wes Diddle (Washington DC, USA), Prof Ranjit Lall (Coventry, England), Prof Kathy Rowan (London, England), as well as the NITRIC trial chief investigator Luregn Schlapbach (Zurich, Switzerland) and editorialist Prof Mark Peters (London, England)

Dr Bronwen Connolly asks cheif investigator Luregn Schlapbach questions from the viewers during the livestream of the NITRIC trial results

BaSICS trial leads Drs Fernando Zampieri & Alexandre Biasi Cavalcante join Rob Mac Sweeney to address some of the questions and comments that arose following the presentation and publication of the BaSICS trial results.

John Marshall and Srinivas Murthy discuss the choice of interventions in the REMAP-CAP adaptive platform trial

Prof Jan Bakker presents the ANDROMEDA-SHOCK trial, comparing peripheral perfusion-guided with serum lactate-guided resuscitation in septic shock

Danny McAuley chairs an international panel discussion on the best critical care trials of 2017, at the Critical Care Reviews Meeting 2018, in Titanic, Belfast.